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St Johns Wort

Hypericum perforatum

About St Johns Wort

St Johns Wort (Hypericum perforatum) is a botanical valued in herbal practice for its contribution to general wellness support. It belongs to the Hypericaceae family, a botanical group with a deep history of medicinal use. Practitioners most often reach for it when working on mood.

St Johns Wort is used in herbal practice for general wellness support, with traditional applications spanning multiple body systems and a long record of use across cultures.

The specific mechanisms underpinning St Johns Wort's activity are still being characterised, though traditional use has consistently pointed toward systemic, gentle support rather than a single targeted action.

Used at typical doses, St Johns Wort carries a favourable safety profile. That said, individual responses vary, and certain populations — including pregnant or nursing people, children, and those with chronic medical conditions — should treat any new botanical with extra caution. Drug-herb interactions are possible with any botanical, particularly for people taking blood thinners, blood-pressure medication, sedatives, or agents metabolised through cytochrome P450 enzymes. As with any botanical supplement, consult a qualified clinician before adding St Johns Wort to your regimen, especially if you are pregnant, nursing, taking prescription medication, or managing a diagnosed condition.

Key Facts

Primary Use
Mood
Evidence Tier
1
Evidence Score
0.50 / 1.00
Typical Dosage
400 mg/day
Plant Family
Hypericaceae

Common Uses

Safety & Considerations

Contraindications
None documented for general adult use. Consult a clinician if pregnant, nursing, or on medication.
Drug Interactions
No major interactions documented. Always disclose herbal supplements to your prescribing physician.

Frequently asked questions

What is St Johns Wort used for?

focus & memory

How much St Johns Wort should I take?

A typical dose is 400 mg/day.

Is St Johns Wort safe?

No major contraindications are documented for general adult use. Consult a clinician if pregnant, nursing, or taking medication.

Build a personalised formula

Use the Evidentia generator to combine St Johns Wort with other evidence-supported herbs tailored to your goals.

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